Potential probiotic (L. plantarum, L. pentosus, P. pentosaceus, W. cibaria and L. rhamnosus) alleviates memory impairment in lipopolysaccharide‐induced cognitive dysfunction and neurotoxicity in mice brain via protection against neuroinflammation and neurodegeneration
Abiola Oluwatosin Obisesan, Samuel O Dodo, Funmilayo Racheal Adeniyi, Juliet Nnenda Olayinka, Olusegun Adebayo Adeoluwa, Adedamola O Fafure · 2025
Read Potential probiotic (L. plantarum, L. pentosus, P. pentosaceus, W. cibaria and L. rhamnosus) alleviates memory impairment in lipopolysaccharide‐induced cognitive dysfunction and neurotoxicity in mice brain via protection against neuroinflammation and neurodegeneration by Abiola Oluwatosin Obisesan, Samuel O Dodo, Funmilayo Racheal Adeniyi, Juliet Nnenda Olayinka, Olusegun Adebayo Adeoluwa, Adedamola O Fafure (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11713413.txt.
Description
Abiola Oluwatosin Obisesan and co-authors test probiotics against brain inflammation in a 2025 mouse paper. A bacterial toxin, LPS, is known to inflame the brain, damage neurons, and impair memory. Probiotic bacteria can rebalance the gut and calm immune activity, but their brain-protective power was little tested.
Forty-eight mice received probiotic strains, a standard memory drug, salt water, or the toxin alone, over seven days. Memory was tested with object and maze tasks. Probiotic-treated mice showed lower levels of inflammatory signals and of a damage marker, and higher levels of a protective antioxidant. A growth factor for neurons rose, while markers of inflammatory cell activation and amyloid fell in key brain regions. The authors conclude the strains may shield memory from toxin-driven harm.
Catalog record
| CREATOR | Abiola Oluwatosin Obisesan, Samuel O Dodo, Funmilayo Racheal Adeniyi, Juliet Nnenda Olayinka, Olusegun Adebayo Adeoluwa, Adedamola O Fafure |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |