Lewy‐related pathology in the Tampere Sudden Death Study
Eloise H Kok, Anders Paetau, Mika Martiskainen, Leo‐Pekka Lyytikäinen, Terho Lehtimäki, Pekka Karhunen, Liisa Myllykangas · 2025
Read Lewy‐related pathology in the Tampere Sudden Death Study by Eloise H Kok, Anders Paetau, Mika Martiskainen, Leo‐Pekka Lyytikäinen, Terho Lehtimäki, Pekka Karhunen, Liisa Myllykangas (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11713395.txt.
Description
Eloise Kok and colleagues measure how common Lewy-related pathology is in Finns who died suddenly outside hospital. This alpha-synuclein buildup underlies Parkinson's disease and related disorders, and early treatment will need to start before symptoms. Brainstem tissue from 562 forensic autopsy cases, aged sixteen to ninety-five, was stained for the protein.
Forty-six cases showed the pathology, and forty-two had Lewy-related changes in the brainstem. The youngest such case was fifty-four, with no known nerve disease. About nine percent of those aged fifty and over were positive, more often men, and rates rose with age. The findings suggest this pathology begins earlier in life than thought.
Catalog record
| CREATOR | Eloise H Kok, Anders Paetau, Mika Martiskainen, Leo‐Pekka Lyytikäinen, Terho Lehtimäki, Pekka Karhunen, Liisa Myllykangas |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |