Lower slow wave sleep and rapid eye‐movement sleep are associated with brain atrophy of AD‐vulnerable regions
Gawon Cho, Adam P Mecca, Orfeu M. Buxton, Xiao Liu, Brienne Miner · 2025
Read Lower slow wave sleep and rapid eye‐movement sleep are associated with brain atrophy of AD‐vulnerable regions by Gawon Cho, Adam P Mecca, Orfeu M. Buxton, Xiao Liu, Brienne Miner (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11713325.txt.
Description
Gawon Cho, Adam Mecca, Orfeu Buxton, Xiao Liu, and Brienne Miner link sleep shape in midlife to brain wear decades later, in a 2025 conference abstract. Poor sleep tracks with higher Alzheimer's risk, but the path from pillow to plaque is unclear. The team read sleep studies from 271 adults in a long-running heart cohort. Brain scans about 17 years later measured regions the disease hits early, plus tiny brain bleeds.
Less deep sleep went with a smaller volume in one of those regions, the lower parietal area. Less dream sleep showed its own links in the full results. The ties held after age, thinking scores, gene risk, and head size were counted. The authors read sleep depth as a possible early lever on brain aging, worth testing in prevention trials.
Catalog record
| CREATOR | Gawon Cho, Adam P Mecca, Orfeu M. Buxton, Xiao Liu, Brienne Miner |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |