Low density lipoprotein receptor related protein 1 regulates adult hippocampal neurogenesis and memory

Kristi Dietert, Nicole Marion, Erzsebet Kokovay, Naomi L Sayre · 2025

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Description

Kristi Dietert and co-authors study a receptor that governs new neuron growth in the adult brain in a 2025 paper. Adult stem cells in the hippocampus keep producing neurons, which supports memory. In Alzheimer's disease that production falters, possibly worsening memory loss.

The receptor, called LRP1, is the subject of the study's title claim: it regulates both neurogenesis and memory. Work of this kind connects a single molecular player to a whole cognitive function. If the receptor can be tuned safely, it might one day help protect memory formation in aging brains.

Catalog record

CREATORKristi Dietert, Nicole Marion, Erzsebet Kokovay, Naomi L Sayre
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11713075

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