Left frontoparietal control network connectivity moderates the effect of amyloid on cognitive decline in preclinical Alzheimer’s disease
Rory Boyle, Zahra Shirzadi, Gillian T Coughlan, Mabel Seto, Michael J Properzi, Hannah M Klinger, Diana L Townsend, Ziwen Yuan, Catherine E Scanlon, Roos J Jutten, Kathryn V Papp, Rebecca E Amariglio, Keith A Johnson, Dorene M Rentz, Jasmeer P Chhatwal, Reisa A Sperling, Aaron P Schultz, Rachel F Bu · 2025
Read Left frontoparietal control network connectivity moderates the effect of amyloid on cognitive decline in preclinical Alzheimer’s disease by Rory Boyle, Zahra Shirzadi, Gillian T Coughlan, Mabel Seto, Michael J Properzi, Hannah M Klinger, Diana L Townsend, Ziwen Yuan, Catherine E Scanlon, Roos J Jutten, Kathryn V Papp, Rebecca E Amariglio, Keith A Johnson, Dorene M Rentz, Jasmeer P Chhatwal, Reisa A Sperling, Aaron P Schultz, Rachel F Bu (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11713058.txt.
Description
Rory Boyle and a large team study brain networks and memory loss before symptoms of Alzheimer disease appear, in work from 2025. Some older adults with amyloid in the brain stay sharp, while others decline. Brain networks that support control of thought may help explain that gap.
The team used a large data set from many sites on care for people without symptoms. They tested whether links in a left control network changed the effect of amyloid on later decline. Other networks were tested as well. The work seeks signs of strength that protect thought, not just signs of disease.
Catalog record
| CREATOR | Rory Boyle, Zahra Shirzadi, Gillian T Coughlan, Mabel Seto, Michael J Properzi, Hannah M Klinger, Diana L Townsend, Ziwen Yuan, Catherine E Scanlon, Roos J Jutten, Kathryn V Papp, Rebecca E Amariglio, Keith A Johnson, Dorene M Rentz, Jasmeer P Chhatwal, Reisa A Sperling, Aaron P Schultz, Rachel F Bu |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |