Diet, APOE‐e4, and cognition in middle‐aged women at increased risk of Alzheimer’s disease

Chadsley M Wessinger, Kyoung Shin Park, Samantha L DuBois, Samuel Kibildis, Hadassah Som‐Pimpong, Jarod C Vance, Brittany D Armstrong, Laurie Wideman, Jennifer L Etnier · 2025

Read Diet, APOE‐e4, and cognition in middle‐aged women at increased risk of Alzheimer’s disease by Chadsley M Wessinger, Kyoung Shin Park, Samantha L DuBois, Samuel Kibildis, Hadassah Som‐Pimpong, Jarod C Vance, Brittany D Armstrong, Laurie Wideman, Jennifer L Etnier (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11713047.txt.

Description

Chadsley Wessinger and co-authors link diet quality to thinking skills in middle-aged women at risk of Alzheimer's disease, in a 2025 study. All the women had a family history of the disease and led inactive lives. A gene variant that raises risk sharply was tested as well. The question was whether better diet goes with better executive function, and whether the gene changes that link.

Just over one hundred women gave diet records, saliva for gene tests, and thinking test scores. Better diet scores predicted better working memory across the group. The benefit, though, showed clearly only in women without the risk variant. For carriers, diet quality showed no clear tie to test scores. The authors note the work is a baseline look from an ongoing trial, not a final word.

Catalog record

CREATORChadsley M Wessinger, Kyoung Shin Park, Samantha L DuBois, Samuel Kibildis, Hadassah Som‐Pimpong, Jarod C Vance, Brittany D Armstrong, Laurie Wideman, Jennifer L Etnier
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11713047

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