Developing an anatomically valid segmentation protocol for anterior regions of the medial temporal lobe

Niyousha Sadeghpour, Sydney A Lim, Anika Wuestefeld, Amanda E Denning, Ranjit Ittyerah, Winifred Trotman, Eunice Chung, Shokufeh Sadaghiani, Karthik Prabhakaran, Madigan Bedard, Daniel T Ohm, Emilio Artacho‐Perula, Maria Mercedes Iniguez de Onzono Martin, Monica Munoz, Francisco Javier Molina Romero · 2025

Read Developing an anatomically valid segmentation protocol for anterior regions of the medial temporal lobe by Niyousha Sadeghpour, Sydney A Lim, Anika Wuestefeld, Amanda E Denning, Ranjit Ittyerah, Winifred Trotman, Eunice Chung, Shokufeh Sadaghiani, Karthik Prabhakaran, Madigan Bedard, Daniel T Ohm, Emilio Artacho‐Perula, Maria Mercedes Iniguez de Onzono Martin, Monica Munoz, Francisco Javier Molina Romero (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11713027.txt.

Description

Niyousha Sadeghpour and a large team of co-authors set out in 2025 to build a better map of the front part of the medial temporal lobe. That brain area is hit early in Alzheimer's disease. Current scan tools often skip the small zones at the front of this area or draw them poorly.

The team built their guide from twenty postmortem cases, matching stained tissue slices to high-field scans of the same brains. An expert marked three small zones by hand, and the team turned those marks into rules that software can apply to standard scans of living people. A shared, sound map should make early disease signs easier to spot and track.

Catalog record

CREATORNiyousha Sadeghpour, Sydney A Lim, Anika Wuestefeld, Amanda E Denning, Ranjit Ittyerah, Winifred Trotman, Eunice Chung, Shokufeh Sadaghiani, Karthik Prabhakaran, Madigan Bedard, Daniel T Ohm, Emilio Artacho‐Perula, Maria Mercedes Iniguez de Onzono Martin, Monica Munoz, Francisco Javier Molina Romero
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11713027

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