The Design of SPRINT MIND and SPRINT MIND 2020
Stephen R Rapp, Mark A Supiano · 2025
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Description
Stephen Rapp and Mark Supiano describe the design of two follow-up studies on blood pressure and the mind in this 2025 paper. The parent trial, SPRINT, tested whether driving systolic pressure below 120, rather than below 140, protects the brain as well as the heart. Its main run ended early, leaving too few dementia cases for a firm verdict.
The trial did show fewer cases of mild cognitive impairment under intensive control. To gain cases and time, two extensions were funded: SPRINT MIND, run in 2017 and 2018, and SPRINT MIND 2020, run through 2023. Of more than ninety-three hundred original participants, over eighty-five hundred took at least one cognitive test. This design paper lays out how dementia and mild impairment were judged, so readers can weigh the coming results.
Catalog record
| CREATOR | Stephen R Rapp, Mark A Supiano |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |