Oral Microbial Dysbiosis Associated with Alzheimer’s Dementia in Puerto Ricans: A Preliminary Report

Hiram Morales, Carlos Alberto Herrero‐Rivera, Cecilia Michelle Soler‐Llompart, Ana Cecilia Sala‐Morales, Gerianne Olivieri‐Henry, Filipa Godoy‐Vitorino, Vanessa Sepulveda · 2025

Read Oral Microbial Dysbiosis Associated with Alzheimer’s Dementia in Puerto Ricans: A Preliminary Report by Hiram Morales, Carlos Alberto Herrero‐Rivera, Cecilia Michelle Soler‐Llompart, Ana Cecilia Sala‐Morales, Gerianne Olivieri‐Henry, Filipa Godoy‐Vitorino, Vanessa Sepulveda (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11712838.txt.

Description

Hiram Morales and co-authors report early results in a 2025 study of mouth bacteria and Alzheimer's disease in Puerto Ricans. New work links the mouth's microbe mix to this brain disease, which is more common in Puerto Rico. A disturbed mix causes gum disease and body wide inflammation, both tied to the disease process. The team compared mouth samples from patients and healthy controls.

Fifty two people took part, twenty eight with the disease and twenty four without. All had health checks, memory tests, and gene testing. Mouth samples were read by gene sequencing. The make up of the bacteria differed clearly between the groups. It also differed across stages of memory loss. Some bacteria were richer in controls, while others linked to inflammation were richer in patients. Amounts tracked with how severe the memory loss was. The authors call the report preliminary.

Catalog record

CREATORHiram Morales, Carlos Alberto Herrero‐Rivera, Cecilia Michelle Soler‐Llompart, Ana Cecilia Sala‐Morales, Gerianne Olivieri‐Henry, Filipa Godoy‐Vitorino, Vanessa Sepulveda
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11712838

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