Associations between sleep apnea and tau in cognitively unimpaired older adults
Victoria R Tennant, Amaryllis A Tsiknia, Carrie B Peltz, Noelle Lee, Maxwell W Hand, Yue Leng, Katie L Stone, Susan Redline, Sid E O'Bryant, Meredith N Braskie, Kristine Yaffe · 2025
Read Associations between sleep apnea and tau in cognitively unimpaired older adults by Victoria R Tennant, Amaryllis A Tsiknia, Carrie B Peltz, Noelle Lee, Maxwell W Hand, Yue Leng, Katie L Stone, Susan Redline, Sid E O'Bryant, Meredith N Braskie, Kristine Yaffe (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11712775.txt.
Description
Victoria Tennant and ten co-authors link sleep apnea to tau buildup in cognitively healthy older adults, in a study from 2025. Aging disrupts sleep and promotes tau deposits in memory regions. Whether apnea measured by device tracks tau beyond those regions was little studied in unimpaired people.
They studied 357 participants from a sleep study with home apnea tests and amyloid and tau brain scans. Groups split at a standard apnea severity threshold. Models adjusted for age, sex, education, background, and a key gene, plus amyloid when predicting tau. Side parietal tau values are among the regional results detailed in the report.
Catalog record
| CREATOR | Victoria R Tennant, Amaryllis A Tsiknia, Carrie B Peltz, Noelle Lee, Maxwell W Hand, Yue Leng, Katie L Stone, Susan Redline, Sid E O'Bryant, Meredith N Braskie, Kristine Yaffe |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |