Induction of Autophagic Pathways in Alzheimer’s Disease via SARS‐CoV‐2 Vaccination: A Deep Learning Analysis of Neurodegenerative Modulation

Rifaldy Fajar, Elfiany Elfiany, Sahnaz V Putri, Prihantini Prihantini · 2025

Read Induction of Autophagic Pathways in Alzheimer’s Disease via SARS‐CoV‐2 Vaccination: A Deep Learning Analysis of Neurodegenerative Modulation by Rifaldy Fajar, Elfiany Elfiany, Sahnaz V Putri, Prihantini Prihantini (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11712765.txt.

Description

Rifaldy Fajar and co-authors present a 2025 study asking whether COVID-19 vaccination could help the brain clear amyloid in Alzheimer's disease. The idea rests on autophagy, the cell's waste-clearing system, which immune activation may switch on. The team used deep learning to search health data for such a pattern.

They followed 1,200 vaccinated patients with early to mid-stage disease and 1,200 matched unvaccinated controls over twenty-four months. Gene, blood, and brain scan data fed their models. Early analysis showed vaccinated patients with higher autophagy markers and lower soluble amyloid than controls, along with slower decline on thinking tests. The authors frame vaccination as a possible new treatment angle.

Catalog record

CREATORRifaldy Fajar, Elfiany Elfiany, Sahnaz V Putri, Prihantini Prihantini
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11712765

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