Gender differences in anticholinergic overactive bladder medication use and the risk of dementia
Kathryn Richardson, Yoon Loke, Nick Steel, Duncan Edwards, Jalesh N Panicker, Stuart Irving, Katharina Mattishent, Chris Fox, Louise Robinson, Irene Petersen · 2025
Read Gender differences in anticholinergic overactive bladder medication use and the risk of dementia by Kathryn Richardson, Yoon Loke, Nick Steel, Duncan Edwards, Jalesh N Panicker, Stuart Irving, Katharina Mattishent, Chris Fox, Louise Robinson, Irene Petersen (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11712707.txt.
Description
Ten authors study bladder drugs and dementia risk by gender in this 2025 paper. Anticholinergic medicines, including those for overactive bladder, have been linked to dementia, but studies often mix up cause and effect and rarely split men from women.
Using English primary care records from 1998 to 2019, the team followed patients over fifty first prescribed one of these bladder drugs. To cut bias, they compared people who received a second prescription within a year with those who got only one, and started the dementia clock carefully to avoid reverse causation. Patients with any prior cognitive trouble were excluded. The design aims at a cleaner read on a widely used drug class.
Catalog record
| CREATOR | Kathryn Richardson, Yoon Loke, Nick Steel, Duncan Edwards, Jalesh N Panicker, Stuart Irving, Katharina Mattishent, Chris Fox, Louise Robinson, Irene Petersen |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |