Characterization of plasma biomarkers of individuals with amyloid‐independent increased tau positron‐emission tomography uptake
Tevy Chan, Joseph Therriault, Yi‐Ting Wang, Etienne Aumont, Jaime Fernandez Arias, Arthur C. Macedo, Nesrine Rahmouni, Stijn Servaes, Lydia Trudel, Seyyed Ali Hosseini, Yansheng Zheng, Kely Monica Quispialaya Socualaya, Sulantha Mathotaarachchi, Jenna Stevenson, Wan Lu Jia, Takashi Matsudaira, Brand · 2025
Read Characterization of plasma biomarkers of individuals with amyloid‐independent increased tau positron‐emission tomography uptake by Tevy Chan, Joseph Therriault, Yi‐Ting Wang, Etienne Aumont, Jaime Fernandez Arias, Arthur C. Macedo, Nesrine Rahmouni, Stijn Servaes, Lydia Trudel, Seyyed Ali Hosseini, Yansheng Zheng, Kely Monica Quispialaya Socualaya, Sulantha Mathotaarachchi, Jenna Stevenson, Wan Lu Jia, Takashi Matsudaira, Brand (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11712649.txt.
Description
Tevy Chan and co-authors study an odd scan pattern in a 2025 Alzheimer's paper. Some people show high tau signal on brain scans without the amyloid buildup that usually pairs with it. That pattern may mark a distinct age related condition driven by tau alone. The team profiled blood markers in people with this pattern to see how they differ.
Blood readouts could sort these cases without a costly scan. They may also show whether the tau only pattern carries the same risk as full Alzheimer's change. The work draws on a large Montreal based cohort and its stored samples. Sorting scan patterns by blood tests would help clinics judge what a lone tau signal means for a patient.
Catalog record
| CREATOR | Tevy Chan, Joseph Therriault, Yi‐Ting Wang, Etienne Aumont, Jaime Fernandez Arias, Arthur C. Macedo, Nesrine Rahmouni, Stijn Servaes, Lydia Trudel, Seyyed Ali Hosseini, Yansheng Zheng, Kely Monica Quispialaya Socualaya, Sulantha Mathotaarachchi, Jenna Stevenson, Wan Lu Jia, Takashi Matsudaira, Brand |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |