Sex differences in the association between pathology and subjective cognitive complaints in the early stages of Alzheimer’s disease

Sophie Boutin, Simona Maria Brambati · 2025

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Description

Sophie Boutin and Simona Maria Brambati present a 2025 study of sex differences in early Alzheimer's disease. Long before clear thinking loss, some people notice their own memory slipping. Those self reported complaints may track with the protein buildup that marks the disease.

The team drew on a large imaging study cohort. They included 418 healthy older adults and 424 people with mild thinking problems. Brain scans sorted each person by whether the marker protein sat above or below a set level. The study then asked how complaints link to the protein in men versus women at each stage. The aim was to sharpen early risk checks.

Catalog record

CREATORSophie Boutin, Simona Maria Brambati
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11712562

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