Understanding cognitive deficits in memory clinic patients with mixed disease by combining plasma markers and advanced diffusion MRI
Anna Dewenter, Amir Dehsarvi, Anna Steward, Davina Biel, Julia Pescoller, Zeyu Zhu, Fabian Wagner, Mattes Gross, Brigitte Nuscher, Sebastian Niclas Roemer, Katharina Buerger, Daniel Janowitz, Michael Ewers, Steffen Tiedt, Martin Dichgans, Matthias Brendel, Nicolai Franzmeier · 2025
Read Understanding cognitive deficits in memory clinic patients with mixed disease by combining plasma markers and advanced diffusion MRI by Anna Dewenter, Amir Dehsarvi, Anna Steward, Davina Biel, Julia Pescoller, Zeyu Zhu, Fabian Wagner, Mattes Gross, Brigitte Nuscher, Sebastian Niclas Roemer, Katharina Buerger, Daniel Janowitz, Michael Ewers, Steffen Tiedt, Martin Dichgans, Matthias Brendel, Nicolai Franzmeier (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11712480.txt.
Description
Anna Dewenter and a large team of co-authors ask what drives memory loss in clinic patients in this 2025 study. Patients at memory clinics often have two problems at once: Alzheimer's disease and damage to the brain's small blood vessels. The team tested whether blood markers and advanced brain scans could tell the two apart.
They studied seventy-six patients with blood tests, thinking tests, and detailed scans. A blood marker tied to Alzheimer's, along with thinning in a known brain region, tracked closely with poor memory for past events. Markers of vessel damage tracked with other kinds of thinking problems instead. The authors argue that pairing blood tests with the right scans can point each patient toward care aimed at the true cause of the decline.
Catalog record
| CREATOR | Anna Dewenter, Amir Dehsarvi, Anna Steward, Davina Biel, Julia Pescoller, Zeyu Zhu, Fabian Wagner, Mattes Gross, Brigitte Nuscher, Sebastian Niclas Roemer, Katharina Buerger, Daniel Janowitz, Michael Ewers, Steffen Tiedt, Martin Dichgans, Matthias Brendel, Nicolai Franzmeier |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |