The Emory‐Sage‐SGC‐JAX TREAT‐AD Center: Target Enabling Packages for Alzheimer’s Disease Emerging Targets
Karina Leal, Alison D. Axtman, Ranjita Betarbet, Paul E Brennan, Gregory W Carter, Haian Fu, Anna K Greenwood, Frank M. Longo, Aled M Edwards, Allan I. Levey, Emory‐Sage‐SGC‐Jax TREAT‐AD Center · 2025
Read The Emory‐Sage‐SGC‐JAX TREAT‐AD Center: Target Enabling Packages for Alzheimer’s Disease Emerging Targets by Karina Leal, Alison D. Axtman, Ranjita Betarbet, Paul E Brennan, Gregory W Carter, Haian Fu, Anna K Greenwood, Frank M. Longo, Aled M Edwards, Allan I. Levey, Emory‐Sage‐SGC‐Jax TREAT‐AD Center (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11712476.txt.
Description
Karina Leal and co-authors describe a center that builds open tool kits for new Alzheimer's drug targets, in a 2025 paper. Dementia touches tens of millions of people, and fresh targets are badly needed. Many candidate proteins lack the probes and tests that let labs judge them.
The center runs a pipeline that ranks targets and builds a package of reagents for each. Packages hold chemical and cell probes that are checked and shared freely. Targets came from large disease consortia lists of understudied proteins. New methods speed ranking, antibody checks, and probe hunting. The authors argue that open tools will hasten the search for drugs against this varied disease.
Catalog record
| CREATOR | Karina Leal, Alison D. Axtman, Ranjita Betarbet, Paul E Brennan, Gregory W Carter, Haian Fu, Anna K Greenwood, Frank M. Longo, Aled M Edwards, Allan I. Levey, Emory‐Sage‐SGC‐Jax TREAT‐AD Center |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |