ß‐Hydroxy ß‐methyl butyrate, a muscle‐building supplement, restores neuronal plasticity in Alzheimer’s disease model
Ramesh Kumar Paidi, Kalipada Pahan · 2025
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Description
Ramesh Kumar Paidi and Kalipada Pahan published a research paper in 2025 on a muscle supplement and its effect on the brains of mice with Alzheimer's-like changes. The supplement, sold to bodybuilders, is known to be safe over long use. The pair asked whether it could also restore the links between brain cells that the disease wears away.
In dishes of mouse brain cells, the supplement raised the levels of proteins that mark strong links between cells. Mice given it by mouth for a month then did better on maze and object tests. Their brains showed more of the same link proteins and more of a signal that helps store memory. The authors suggest a common gym aid merits more study.
Catalog record
| CREATOR | Ramesh Kumar Paidi, Kalipada Pahan |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |