Understanding apathy: behavioral and neural correlates of apathy in neurodegenerative disorders

Neke Nsor, Casey Brown · 2025

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Description

Neke Nsor and Casey Brown study apathy in brain diseases in a 2025 paper. Apathy means lost motivation and flattened feeling, and it burdens many dementia patients. Four hundred thirty-four people, spanning diagnosed patients, at-risk adults, and healthy controls, took brain scans, thinking tests, and emotion ratings from caregivers.

Greater apathy tracked with weaker positive emotion and poorer emotion reading, even after many adjustments. It did not track with negative emotion. Brain scans tied apathy to shrinkage in reward and salience hubs, while poor emotion reading tied to face-processing areas. Readers get a finer split of apathy's roots.

Catalog record

CREATORNeke Nsor, Casey Brown
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11712440

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