Predicting Cognitive Decline: A Comprehensive Study On relative Brain Age, Cognitive Reserve, And Longitudinal Changes

Mahboubeh Motaghi, Olivier Potvin, Valérie Turcotte, Iman Beheshti, Simon Duchesne · 2025

Read Predicting Cognitive Decline: A Comprehensive Study On relative Brain Age, Cognitive Reserve, And Longitudinal Changes by Mahboubeh Motaghi, Olivier Potvin, Valérie Turcotte, Iman Beheshti, Simon Duchesne (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11712394.txt.

Description

Mahboubeh Motaghi and co-authors explore brain age in a 2025 study of memory loss. Brain age is read from MRI scans, and relative brain age compares one person's brain with others of the same age. A brain that looks older than its years has been tied to poor health and faster decline.

The team tracked healthy adults and people with mild memory loss for up to five years. In the memory loss group, relative brain age helped predict change in word recall and other skills. Machine learning models forecast test scores with small errors. The authors also link brain age with cognitive reserve, the buffer built by schooling, work, and verbal skill.

Catalog record

CREATORMahboubeh Motaghi, Olivier Potvin, Valérie Turcotte, Iman Beheshti, Simon Duchesne
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11712394

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