The interaction between dietary habits, BDNF, CCK, and gut microbiota in the pathophysiology of Alzheimer’s disease
Caitlin E Montgomery, Jessica Arango Hipsley, Olivia Schuh, Anjali Shah, Deepesh Khanna · 2025
Read The interaction between dietary habits, BDNF, CCK, and gut microbiota in the pathophysiology of Alzheimer’s disease by Caitlin E Montgomery, Jessica Arango Hipsley, Olivia Schuh, Anjali Shah, Deepesh Khanna (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11712382.txt.
Description
Caitlin Montgomery and co-authors review how diet, gut microbes, and two body chemicals interact in Alzheimer's disease. One chemical, BDNF, supports neuron growth and plasticity. The other, CCK, is a fullness hormone that also steers BDNF levels. Both shift in the disease, the review notes.
Their 2025 review searched major databases for studies from 2012 to 2024 that link these chemicals to food, exercise, or gut microbes in Alzheimer's patients. Exercise clearly raised BDNF levels in patients, the literature suggests. A high fat Western style diet lowered BDNF in mice. Gut microbe ties to the disease showed up in both human and mouse work. The authors map the web of links.
Catalog record
| CREATOR | Caitlin E Montgomery, Jessica Arango Hipsley, Olivia Schuh, Anjali Shah, Deepesh Khanna |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |