Correlation of Clinical and Imaging Findings in Early‐Onset Alzheimer's Patients with Distinct Initial Symptoms
Sinem Özçelik, Pınar Yiğit, Tolga Can Bozdemir, Gamze Çapa Kaya, Zerrin Yildirim, Boon Lead Tee, Hakan Gurvit, Görsev Yener, Maria Luisa Gorno Tempini, Didem Öz · 2025
Read Correlation of Clinical and Imaging Findings in Early‐Onset Alzheimer's Patients with Distinct Initial Symptoms by Sinem Özçelik, Pınar Yiğit, Tolga Can Bozdemir, Gamze Çapa Kaya, Zerrin Yildirim, Boon Lead Tee, Hakan Gurvit, Görsev Yener, Maria Luisa Gorno Tempini, Didem Öz (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11712358.txt.
Description
Sinem Özçelik and co-authors compare symptoms and scan findings in early-onset Alzheimer's disease in a 2025 study. The early form, which starts before old age, often begins with language, vision, or behavior trouble rather than memory loss. The team reviewed nineteen patients whose spinal fluid confirmed the disease.
Patients fell into groups by first symptom: memory, vision and space, language, or behavior. Test scores lined up with activity on PET scans in matching brain areas. Memory scores, for example, tracked left temporal activity in the memory group. Attention scores set the language and memory groups apart. The authors say these links show how varied the early form is, and they argue for care plans fitted to each patient's pattern.
Catalog record
| CREATOR | Sinem Özçelik, Pınar Yiğit, Tolga Can Bozdemir, Gamze Çapa Kaya, Zerrin Yildirim, Boon Lead Tee, Hakan Gurvit, Görsev Yener, Maria Luisa Gorno Tempini, Didem Öz |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |