Maternal Care and Offspring Development Trajectories in Mice: Effects of Alzheimer’s Disease Genotype and Maternal Age
Alesia V Prakapenka, Sophia Parpala, Mallica Cary, Edith Ramirez, Stacy Kujawa, Andrew Hawkey · 2025
Read Maternal Care and Offspring Development Trajectories in Mice: Effects of Alzheimer’s Disease Genotype and Maternal Age by Alesia V Prakapenka, Sophia Parpala, Mallica Cary, Edith Ramirez, Stacy Kujawa, Andrew Hawkey (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11712353.txt.
Description
Alesia Prakapenka and co-authors study mothering in mice bred for dementia research in this 2025 paper. Birth changes the female body and brain, and past findings on birth and dementia risk clash. Age at first birth may be one hidden factor, so the team starts by mapping care in young mothers.
Two mouse strains, one with dementia-linked genes and one normal, gave birth at two months of age. Staff tracked weight gain, litter size, and how fast mothers fetched pups back to the nest. Dementia-strain mothers slowed as more pups were fetched, and they dug more during the task. Their pups also grew skills on a unlike track. Work with older mothers is still under way.
Catalog record
| CREATOR | Alesia V Prakapenka, Sophia Parpala, Mallica Cary, Edith Ramirez, Stacy Kujawa, Andrew Hawkey |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |