FDG‐PET patterns of LATE & co: disentangling the pathological heterogeneity of Tau‐negative amnestic syndromes
Jesús Silva‐Rodríguez, Alexis Moscoso, Miguel Labrador‐Espinosa, Pascual Sanchez‐Juan, Michael Schöll, Michel J Grothe · 2025
Read FDG‐PET patterns of LATE & co: disentangling the pathological heterogeneity of Tau‐negative amnestic syndromes by Jesús Silva‐Rodríguez, Alexis Moscoso, Miguel Labrador‐Espinosa, Pascual Sanchez‐Juan, Michael Schöll, Michel J Grothe (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11712301.txt.
Description
Jesús Silva-Rodríguez and colleagues sort memory syndromes that lack tau signs with brain scans, in work from 2025. Many patients with a clinical Alzheimer's label do not meet tissue rules for the disease. A condition called LATE is a leading alternative in older patients and has a known scan pattern in limbic areas.
The study used three hundred sixty impaired patients with both tau and glucose based scans. Close to half were rated tau negative by visual reading. Among those with clear low metabolism areas, about two fifths fit the LATE like pattern. Clustering of the rest suggested other diseases, including semantic and Lewy body patterns. The LATE like group was older and had worse memory scores.
Catalog record
| CREATOR | Jesús Silva‐Rodríguez, Alexis Moscoso, Miguel Labrador‐Espinosa, Pascual Sanchez‐Juan, Michael Schöll, Michel J Grothe |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |