APOE‐ε4 associations with smartphone‐based cognitive markers
Anna M Rosická, Sol Fittipaldi, Eoghan Gallagher, Anna K Hanlon, Agustín Ibáñez, Katie Bridgeman, Graciela Muniz‐Terrera, Karen Ritchie, Craig W Ritchie, John T O'Brien, Ivan Koychev, Brian Lawlor, Lorina Naci, Claire M Gillan · 2025
Read APOE‐ε4 associations with smartphone‐based cognitive markers by Anna M Rosická, Sol Fittipaldi, Eoghan Gallagher, Anna K Hanlon, Agustín Ibáñez, Katie Bridgeman, Graciela Muniz‐Terrera, Karen Ritchie, Craig W Ritchie, John T O'Brien, Ivan Koychev, Brian Lawlor, Lorina Naci, Claire M Gillan (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11712058.txt.
Description
Anna Rosicka and co-authors tested whether phone-based thinking tests reflect a gene risk for dementia, in this 2025 study. Carrying one gene variant raises risk, but its effect may differ by skill. Past work found strong harm on navigation tasks and mixed results elsewhere.
The study enrolled 87 healthy adults aged 44 to 67 who knew their gene status. They played game-like tasks on a phone app that tested planning, visual memory, speed, and flexible thought, plus self-ratings of memory. Carriers did not score worse overall. In raw checks they even scored better on visual memory, though that link faded after full adjustment. The authors urge care in reading phone tests as gene risk signs.
Catalog record
| CREATOR | Anna M Rosická, Sol Fittipaldi, Eoghan Gallagher, Anna K Hanlon, Agustín Ibáñez, Katie Bridgeman, Graciela Muniz‐Terrera, Karen Ritchie, Craig W Ritchie, John T O'Brien, Ivan Koychev, Brian Lawlor, Lorina Naci, Claire M Gillan |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |