Hormonal Therapy and Cardiovascular Health
Farzin Khosrow-Khavar, Laurent Azoulay · 2024
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Description
Farzin Khosrow-Khavar and Laurent Azoulay comment on the heart safety of hormonal therapy for breast cancer, where heart disease is now a leading cause of death among survivors. In hormone-sensitive cancers, aromatase inhibitors and tamoxifen are standard long-term drugs. Trials in older women linked the inhibitors to more heart disease than tamoxifen, but younger women were understudied.
They discuss a large real-world study of younger women that matched over a thousand patients on inhibitors plus ovarian suppression with about five thousand on tamoxifen. Over a median of about a year and a half, the inhibitor strategy carried roughly double the heart disease hazard. The commentary weighs what this means for treating younger patients.
Catalog record
| CREATOR | Farzin Khosrow-Khavar, Laurent Azoulay |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 7 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |