Digitally Assessed Sleep Disturbances for Early Diagnosis of Alzheimer’s Disease

Sophia Krix, Joud Odeh, Manuel Lentzen, Andrea Val‐Guardiola, Neus Falgàs Martínez, Alankar Atreya, Pauline Conde, Aiden Doherty, Srinivasan Vairavan, Marijn Muurling, Casper de Boer, Jelena Curcic, Margarita Grammatikopoulou, Spiros Nikolopoulos, Anna‐Katharine Brem, Neva Coello, Vaibhav Narayan, G · 2025

Read Digitally Assessed Sleep Disturbances for Early Diagnosis of Alzheimer’s Disease by Sophia Krix, Joud Odeh, Manuel Lentzen, Andrea Val‐Guardiola, Neus Falgàs Martínez, Alankar Atreya, Pauline Conde, Aiden Doherty, Srinivasan Vairavan, Marijn Muurling, Casper de Boer, Jelena Curcic, Margarita Grammatikopoulou, Spiros Nikolopoulos, Anna‐Katharine Brem, Neva Coello, Vaibhav Narayan, G (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11711964.txt.

Description

Sophia Krix and co-authors test whether sleep tracked by devices can flag early Alzheimer's disease. Sleep trouble and the disease feed each other, so sleep may serve as an early sign. The team modeled sleep from wearable and bedside devices in a European cohort. Math models tracked how long each sleep stage lasts and how stages hand off.

Patients at each disease stage lingered longer in light sleep and waking, and less in dream sleep. Middle stage patients also bounced into light sleep and then woke more often. One wrist device split healthy people from the earliest stage on its own. Question forms alone did not. The work is early but points to a cheap home test.

Catalog record

CREATORSophia Krix, Joud Odeh, Manuel Lentzen, Andrea Val‐Guardiola, Neus Falgàs Martínez, Alankar Atreya, Pauline Conde, Aiden Doherty, Srinivasan Vairavan, Marijn Muurling, Casper de Boer, Jelena Curcic, Margarita Grammatikopoulou, Spiros Nikolopoulos, Anna‐Katharine Brem, Neva Coello, Vaibhav Narayan, G
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11711964

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