Extracellular‐Vesicle mediated pyroptosis leads to gut‐brain axis after stroke in a mouse model of Alzheimer’s Disease
Nadine A Kerr, Alfredo Fernandez Higueras, Juliana Sanchez‐Molano, Winston Walters, Juan Pablo de Rivero Vaccari, Robert W Keane, Helen M Bramlett, W Dalton Dietrich · 2025
Read Extracellular‐Vesicle mediated pyroptosis leads to gut‐brain axis after stroke in a mouse model of Alzheimer’s Disease by Nadine A Kerr, Alfredo Fernandez Higueras, Juliana Sanchez‐Molano, Winston Walters, Juan Pablo de Rivero Vaccari, Robert W Keane, Helen M Bramlett, W Dalton Dietrich (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11710799.txt.
Description
Nadine Kerr and co-authors report a 2025 study on how stroke affects the gut and brain in mice bred to model Alzheimer disease. People with stroke or Alzheimer disease who also have gut problems often fare worse. The team asked whether tiny packets released by cells carry a cell-death signal between gut and brain after stroke.
Aged mice of the model strain and normal mice had a stroke caused by light and a dye. A day later, gut and brain tissue showed signs of the fiery cell-death pathway. Gut leak tests and brain damage measures followed. The work traces one route of gut-brain harm after stroke.
Catalog record
| CREATOR | Nadine A Kerr, Alfredo Fernandez Higueras, Juliana Sanchez‐Molano, Winston Walters, Juan Pablo de Rivero Vaccari, Robert W Keane, Helen M Bramlett, W Dalton Dietrich |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |