Chronic traumatic encephalopathy neuropathologic change is associated with higher stage limbic‐predominant age‐related TDP‐43 encephalopathy
Hailong Song, Kamar E Ameen‐Ali, Claire Kennedy‐Dietrich, Jean‐Pierre Dolle, Eddie B Lee, Douglas H Smith, William Stewart · 2025
Read Chronic traumatic encephalopathy neuropathologic change is associated with higher stage limbic‐predominant age‐related TDP‐43 encephalopathy by Hailong Song, Kamar E Ameen‐Ali, Claire Kennedy‐Dietrich, Jean‐Pierre Dolle, Eddie B Lee, Douglas H Smith, William Stewart (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11710791.txt.
Description
Brain researchers report a study of two kinds of protein buildup seen after head injury and in old age. One is linked to repeated mild brain injury and is called CTE change. The other involves a protein known as TDP-43 and grows worse in stages with age. The team asked how often the second kind appears with the first, and how far it spreads in the brain.
The team checked brain tissue from people in a shared archive. The group held 30 people with past repeated injury and illness, plus control cases with and without illness. Staff mapped stained slides to track the protein in each case. The TDP-43 signs were found in about 40 percent of the injury group. Higher stage disease of that kind tracked with the CTE change named in the title.
Catalog record
| CREATOR | Hailong Song, Kamar E Ameen‐Ali, Claire Kennedy‐Dietrich, Jean‐Pierre Dolle, Eddie B Lee, Douglas H Smith, William Stewart |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |