Involvement of the choroid plexus in Alzheimer’s disease pathophysiology: A mouse and human proteomic study
Aurore Delvenne, Charysse Vandendriessche, Johan Gobom, Marlies Burgelman, Pieter Dujardin, Clint De Nolf, Betty M. Tijms, Suzanne E. Schindler, Frans R.J. Verhey, Inez H.G.B. Ramakers, Henrik Zetterberg, Pieter Jelle Visser, Roosmarijn E Vandenbroucke, Stephanie J. B. Vos, EMIF‐AD MBD study group · 2025
Read Involvement of the choroid plexus in Alzheimer’s disease pathophysiology: A mouse and human proteomic study by Aurore Delvenne, Charysse Vandendriessche, Johan Gobom, Marlies Burgelman, Pieter Dujardin, Clint De Nolf, Betty M. Tijms, Suzanne E. Schindler, Frans R.J. Verhey, Inez H.G.B. Ramakers, Henrik Zetterberg, Pieter Jelle Visser, Roosmarijn E Vandenbroucke, Stephanie J. B. Vos, EMIF‐AD MBD study group (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11710753.txt.
Description
Aurore Delvenne and co-authors study a small brain structure in 2025 for its role in Alzheimer disease. The structure, the choroid plexus, makes the fluid that bathes the brain, and it changes in the disease, though its part in the process is unclear. The team reads protein patterns in the structure in mice and compares them with human fluid data.
Mice bred to develop amyloid buildup showed protein shifts in the structure at both young and old ages. The shifts touched cell lining, energy parts, protein handling, and fat pathways. Matching patterns in human spinal fluid data from nearly five hundred people point to shared routes. The study frames the structure as an active player worth more study.
Catalog record
| CREATOR | Aurore Delvenne, Charysse Vandendriessche, Johan Gobom, Marlies Burgelman, Pieter Dujardin, Clint De Nolf, Betty M. Tijms, Suzanne E. Schindler, Frans R.J. Verhey, Inez H.G.B. Ramakers, Henrik Zetterberg, Pieter Jelle Visser, Roosmarijn E Vandenbroucke, Stephanie J. B. Vos, EMIF‐AD MBD study group |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |