Application of restricted mean survival time method in Clinical Trials for Alzheimer disease
Guogen Shan · 2025
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Description
Guogen Shan adapts a survival yardstick to Alzheimer trials in a 2025 paper. Restricted mean survival time gives the average time a patient holds a state up to a set visit, a read out that is easy to grasp. Trials for Alzheimer disease care about time saved as illness creeps forward.
Shan builds a twin scale, restricted mean disease progression, on that same base. Two new methods on the scale then gauge time saved by a drug. Tests show their mean squared error runs about a third below the older methods. The gain means time saved claims in such trials can be stated with more trust.
Catalog record
| CREATOR | Guogen Shan |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 912 bytes |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |