Language impairment associated with prognosis in progressive supranuclear palsy

Indira Ruth Garcia Cordero, Mohsen Hadian, Ece Bayram, Federico Rodriguez‐Porcel, Christopher Stephen, Alex Pantelyat, Jay Iyer, Tao Xie, Adam L Boxer, Douglas Gunzler, Marian Dale, Nikolaus McFarland, Kyurim Kang, Matthew Swan, Anne‐Marie Wills, Anthony E Lang, Maria Carmela Tartaglia · 2025

Read Language impairment associated with prognosis in progressive supranuclear palsy by Indira Ruth Garcia Cordero, Mohsen Hadian, Ece Bayram, Federico Rodriguez‐Porcel, Christopher Stephen, Alex Pantelyat, Jay Iyer, Tao Xie, Adam L Boxer, Douglas Gunzler, Marian Dale, Nikolaus McFarland, Kyurim Kang, Matthew Swan, Anne‐Marie Wills, Anthony E Lang, Maria Carmela Tartaglia (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11710289.txt.

Description

Indira Ruth Garcia Cordero and a large team of co-authors test whether language scores predict decline in a brain disease in a 2025 paper. Progressive supranuclear palsy harms movement severely, and language problems are common but often overlooked beside the motor signs. The team used data from a drug trial with nearly one hundred fifty patients tested at entry and eight months later.

Language, memory, and executive scores all tracked together at entry. Only the language score, though, predicted how much worse patients' disease rating became, while memory and executive scores did not. Loss of tissue in language areas of the brain also predicted language decline. The authors argue language testing deserves a central place in tracking this disease.

Catalog record

CREATORIndira Ruth Garcia Cordero, Mohsen Hadian, Ece Bayram, Federico Rodriguez‐Porcel, Christopher Stephen, Alex Pantelyat, Jay Iyer, Tao Xie, Adam L Boxer, Douglas Gunzler, Marian Dale, Nikolaus McFarland, Kyurim Kang, Matthew Swan, Anne‐Marie Wills, Anthony E Lang, Maria Carmela Tartaglia
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE3 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11710289

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