Examining the Association Between Differences in Post Turning Driving Behavior on a Driving Simulator and Amyloid Status in Cognitively Normal Older Adults

Description

Savannah G Rose and seven colleagues compare driving in a simulator, published in 2025, between older adults with and without brain amyloid. People with thinking problems face higher crash risk, but amyloid can build up years before any symptoms. The team asked whether driving differs in healthy people who already carry that buildup. They focused on what drivers do right after a left turn.

Seventy-three adults aged sixty-five and older took a twenty-minute simulator drive. Brain scans split them into amyloid positive and negative groups. After the turn, the positive group drove more slowly and stayed closer to the lane center. They also made fewer errors, both off-road and toward oncoming traffic. The authors read this as more careful driving, perhaps from lower confidence. They say such small changes might flag early disease processes.

Catalog record

Source: https://europepmc.org/articles/PMC11710216