Association between short‐term memory binding performance and tau burden in the medial temporal lobe
Lara Huyghe, Lisa Quenon, Yasmine Salman, Lise Colmant, Thomas Gérard, Vincent Malotaux, Emilien Boyer, Laurence Dricot, Renaud Lhommel, Adrian Ivanoiu, Bernard J Hanseeuw · 2025
Read Association between short‐term memory binding performance and tau burden in the medial temporal lobe by Lara Huyghe, Lisa Quenon, Yasmine Salman, Lise Colmant, Thomas Gérard, Vincent Malotaux, Emilien Boyer, Laurence Dricot, Renaud Lhommel, Adrian Ivanoiu, Bernard J Hanseeuw (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11710206.txt.
Description
Lara Huyghe and co-authors test a memory skill in early Alzheimer disease in a 2025 paper. Holding linked features of an object in mind, such as shape plus color, rests on a deep brain region hit early by tau buildup. Whether that skill slips before symptoms, and tracks tau there, was not settled.
Three groups took a short-term memory test with shape-only and shape-plus-color rounds. People with amyloid buildup, with or without mild problems, scored lower than amyloid-free peers in most rounds. Tau load in the deep region tracked total scores across all comers and among the healthy group alone. The link ran stronger for the binding rounds. The authors propose the test as an early marker.
Catalog record
| CREATOR | Lara Huyghe, Lisa Quenon, Yasmine Salman, Lise Colmant, Thomas Gérard, Vincent Malotaux, Emilien Boyer, Laurence Dricot, Renaud Lhommel, Adrian Ivanoiu, Bernard J Hanseeuw |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |