Potentially heritable biomarkers of neurodegeneration in a marmoset model of Alzheimer’s disease
Sonal Kumar, Catrina Spruce, Annat Haber, Laura Schultz, Hasi Huhe, Takeshi Murai, Sang‐Ho Choi, Stephanie Hachem, Yongshan Mou, Seung‐Kwon Ha, Jung Eun Park, Lauren Bailey, Lauren Mongeau, Andrew DeSana, Brianne Stein, Lauren K Hayrynen Schaeffer, Gregg E Homanics, Afonso C Silva, Stacey J Sukoff R · 2025
Read Potentially heritable biomarkers of neurodegeneration in a marmoset model of Alzheimer’s disease by Sonal Kumar, Catrina Spruce, Annat Haber, Laura Schultz, Hasi Huhe, Takeshi Murai, Sang‐Ho Choi, Stephanie Hachem, Yongshan Mou, Seung‐Kwon Ha, Jung Eun Park, Lauren Bailey, Lauren Mongeau, Andrew DeSana, Brianne Stein, Lauren K Hayrynen Schaeffer, Gregg E Homanics, Afonso C Silva, Stacey J Sukoff R (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11710181.txt.
Description
Sonal Kumar and a large team share a 2025 conference abstract on marmoset monkeys as a model of Alzheimer's disease. Marmosets age fast for primates, which lets researchers track disease markers across life. The team sequenced genomes in a colony with a few carriers of a disease-linked gene variant and measured many markers of brain degeneration.
Marker links ran stronger in females than in males. Tau, a nerve damage marker, an astrocyte marker, and amyloid measures all moved together in females. The team also found variants at gene sites that human studies have tied to the disease. Such shared patterns may mark traits passed through families.
Catalog record
| CREATOR | Sonal Kumar, Catrina Spruce, Annat Haber, Laura Schultz, Hasi Huhe, Takeshi Murai, Sang‐Ho Choi, Stephanie Hachem, Yongshan Mou, Seung‐Kwon Ha, Jung Eun Park, Lauren Bailey, Lauren Mongeau, Andrew DeSana, Brianne Stein, Lauren K Hayrynen Schaeffer, Gregg E Homanics, Afonso C Silva, Stacey J Sukoff R |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |