‘Dependence’ as a meaningful patient‐focused outcome in Alzheimer’s disease: Qualitative concept elicitation and cognitive debriefing of the Dependence Scale in early symptomatic AD
Alexandra Atkins, Laure Delbecque, Emma Elliott, Phoebe Heinrich, Stefan Cano, Yaakov Stern · 2025
Read ‘Dependence’ as a meaningful patient‐focused outcome in Alzheimer’s disease: Qualitative concept elicitation and cognitive debriefing of the Dependence Scale in early symptomatic AD by Alexandra Atkins, Laure Delbecque, Emma Elliott, Phoebe Heinrich, Stefan Cano, Yaakov Stern (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11710031.txt.
Description
Alexandra Atkins and co-authors ask what dependence means in early Alzheimer disease in a 2025 paper. Dependence, how much help a patient needs, may sum the whole weight of the disease. Its sense in the first stages had not been asked of carers.
Talks with carers of mild stage patients drew out what dependence means to them. A thirteen item scale, filled by carer talk, was then checked line by line. New guide notes that clear vague items were also tried. Carers backed the scale as a true gauge of daily need. Trial teams can thus use it with more trust.
Catalog record
| CREATOR | Alexandra Atkins, Laure Delbecque, Emma Elliott, Phoebe Heinrich, Stefan Cano, Yaakov Stern |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |