The neurophysiological effects of frontotemporal lobar degeneration: linking synaptic loss, network connectivity and cognitive decline
James B Rowe · 2025
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Description
James Rowe links synapse loss, network faults, and thinking decline in frontotemporal brain illnesses in a 2025 conference paper. The group covers a conduct led dementia and a palsy with stiff movement. Their proteins differ, yet both poison synapses and drain a calming brain chemical.
Rowe's team used brain wave gear, a synapse scan, and standard scans on patients and controls. The conduct led group showed deep synapse loss that tracked tightly with thinking scores. The palsy group lost synapses too, and the loss grew over twelve months and matched slide in function. In both, synapse loss outran plain shrinkage and matched breaks in brain networks. Wave tasks caught odd responses to surprise tones. The work ties scales from cell to clinic.
Catalog record
| CREATOR | James B Rowe |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |