Butyrate and Lauric acid effect on Astrocytes and Neurons in Alzheimer’s disease

RM Uththara Sachinthanie Senarath, Lotta E Oikari, Prashant Bharadwaj, Vijay Jayasena, Ralph N Martins, Warnakulasuriya Mary Ann Dipika Binosha Fernando · 2025

Read Butyrate and Lauric acid effect on Astrocytes and Neurons in Alzheimer’s disease by RM Uththara Sachinthanie Senarath, Lotta E Oikari, Prashant Bharadwaj, Vijay Jayasena, Ralph N Martins, Warnakulasuriya Mary Ann Dipika Binosha Fernando (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11709681.txt.

Description

Uththara Sachinthanie Senarath and five co-authors present a 2025 study of two dietary fats and their effects on brain cells in Alzheimer's disease. Inflammation in the brain is a core part of the disease. One fat is a short chain type made by gut microbes; the other is a medium chain fat found in coconut oil.

Past work hints both fats calm inflammation, cut the harm of the disease's plaque protein, and help cell power plants work. How each fat switches the brain's support cells and neurons on or off was unclear. The team tested the fats alone and together, including against plaque driven activation of the cells.

Catalog record

CREATORRM Uththara Sachinthanie Senarath, Lotta E Oikari, Prashant Bharadwaj, Vijay Jayasena, Ralph N Martins, Warnakulasuriya Mary Ann Dipika Binosha Fernando
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11709681

Browse the full library · About the Tower of Babel