Psychological profiles associated with cortical thickness changes in middle‐aged adults
David Bartrés‐Faz, Harriet Demnitz‐King, María Cabello‐Toscano, Lídia Vaqué‐Alcázar, Rob Saunders, Gabriele Cattaneo, Núria Bargalló, Josep M. Tormos‐Muñoz, Javier Solana Sánchez, Alvaro Pascual‐Leone, Natalie L. Marchant · 2025
Read Psychological profiles associated with cortical thickness changes in middle‐aged adults by David Bartrés‐Faz, Harriet Demnitz‐King, María Cabello‐Toscano, Lídia Vaqué‐Alcázar, Rob Saunders, Gabriele Cattaneo, Núria Bargalló, Josep M. Tormos‐Muñoz, Javier Solana Sánchez, Alvaro Pascual‐Leone, Natalie L. Marchant (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11709504.txt.
Description
Bartrés-Faz and co-authors sort middle aged adults by their mix of mental risk and protective traits, then watch how their brains age. Gloomy rumination and stress raise dementia risk, while purpose and mindfulness may guard. Their 2025 study profiles 742 healthy adults in Barcelona and follows brain scans for over two years in most.
Three profiles emerged: one low on protective traits, one high on risk traits, and one, the largest, rich in protection with modest risk. The low protection group lost cortical thickness faster in temporal areas that match the Alzheimer thinning pattern, compared with the protected group. Extra checks against anxiety and depression kept the contrast. The authors argue that trait mixes, visible by midlife, already track with brain change.
Catalog record
| CREATOR | David Bartrés‐Faz, Harriet Demnitz‐King, María Cabello‐Toscano, Lídia Vaqué‐Alcázar, Rob Saunders, Gabriele Cattaneo, Núria Bargalló, Josep M. Tormos‐Muñoz, Javier Solana Sánchez, Alvaro Pascual‐Leone, Natalie L. Marchant |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 3 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |