Comparative Efficacy of Semaglutide Versus Liraglutide or Efinopegdutide on Weight Loss in Obese Patients: A Systematic Review and Meta-Analysis
Jimmy Wen, Christiane How-Volkman, Alina Truong, Denise Nadora, Ethan M Bernstein, Muzammil Akhtar, Jose Puglisi, Eldo Frezza · 2024
Read Comparative Efficacy of Semaglutide Versus Liraglutide or Efinopegdutide on Weight Loss in Obese Patients: A Systematic Review and Meta-Analysis by Jimmy Wen, Christiane How-Volkman, Alina Truong, Denise Nadora, Ethan M Bernstein, Muzammil Akhtar, Jose Puglisi, Eldo Frezza (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11704649.txt.
Description
Jimmy Wen and seven colleagues compare heavyweight weight-loss drugs head to head for people with obesity but not diabetes. GLP-1 drugs made their name in diabetes care. Which one trims the most weight in plain obesity, and at what side-effect cost, needed a direct answer.
The review gathered direct comparison trials of semaglutide against liraglutide and against efinopegdutide. Pooled results gave semaglutide a clear edge over liraglutide in mean weight lost. Against efinopegdutide the gap was not firm. All three drugs were tolerated much the same, with mostly mild to moderate gut complaints. The authors call for more direct trials against the newer multi-target drugs.
Catalog record
| CREATOR | Jimmy Wen, Christiane How-Volkman, Alina Truong, Denise Nadora, Ethan M Bernstein, Muzammil Akhtar, Jose Puglisi, Eldo Frezza |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |