EXPLORING EPIGENETIC CLOCKS AND COGNITIVE CHANGE IN MIDDLE ADULTHOOD
Daisy Zavala, Zita Oravecz, Jennifer Graham-Engeland, Christopher Engeland, Martin Sliwinski, Krishna Veeramah, Stacey Scott · 2024
Read EXPLORING EPIGENETIC CLOCKS AND COGNITIVE CHANGE IN MIDDLE ADULTHOOD by Daisy Zavala, Zita Oravecz, Jennifer Graham-Engeland, Christopher Engeland, Martin Sliwinski, Krishna Veeramah, Stacey Scott (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11693117.txt.
Description
Daisy Zavala and co-authors study, in a 2024 paper, whether a blood-based aging measure tracks how thinking skills change in midlife. The measure uses chemical marks on DNA to estimate a person's biological age. When that age runs ahead of the real age, earlier work linked it to worse average mental scores and more uneven day-to-day performance.
The team followed 142 midlife adults across four yearly waves, testing processing speed and working memory with phone-based tasks. Five DNA aging clocks supplied the aging measure. People with faster biological aging had slower peak scores at the first wave, as did older people. Yet neither measure predicted how peak scores changed over time. Faster aging did go with more score swings across the study, while real age tracked forgetting between waves in one task.
Catalog record
| CREATOR | Daisy Zavala, Zita Oravecz, Jennifer Graham-Engeland, Christopher Engeland, Martin Sliwinski, Krishna Veeramah, Stacey Scott |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |