ASSOCIATION OF IMMUNE CELLS AND INFLAMMATORY BIOMARKERS WITH DEPRESSIVE SYMPTOMS IN THE FRAMINGHAM HEART STUDY

Sandhya Iyer, Yumeng Cao, Kathryn Lunetta, Ryan Liebegott, Margaret Doyle, Jiachen Chen, Ahmed Ragab, Joanne Murabito · 2024

Read ASSOCIATION OF IMMUNE CELLS AND INFLAMMATORY BIOMARKERS WITH DEPRESSIVE SYMPTOMS IN THE FRAMINGHAM HEART STUDY by Sandhya Iyer, Yumeng Cao, Kathryn Lunetta, Ryan Liebegott, Margaret Doyle, Jiachen Chen, Ahmed Ragab, Joanne Murabito (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11692198.txt.

Description

Sandhya Iyer and seven co-authors published a study in 2024 on the association of immune cells and inflammatory biomarkers with depressive symptoms in a long-running heart study in the United States. Depression is common and has a substantial impact on older adults. Immune dysfunction has been proposed as one mechanism behind its symptoms, which could open new targeted treatments.

The study drew on 996 adults with an average age of sixty-two, over half of them women. Only a share scored in the range indicating symptoms on the scale used. One growth factor measured in the blood was associated with higher symptom scores. A ratio of two immune cell types trended the opposite way. One inflammatory marker trended with the high-score group. The team describes the two findings as hints rather than proof, and the work shows how wide a net this field needs to cast.

Catalog record

CREATORSandhya Iyer, Yumeng Cao, Kathryn Lunetta, Ryan Liebegott, Margaret Doyle, Jiachen Chen, Ahmed Ragab, Joanne Murabito
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11692198

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