CELL SENESCENCE AND MITOCHONDRIA: A MATTER OF LIFE OR DEATH
Joao Passos · 2024
Read CELL SENESCENCE AND MITOCHONDRIA: A MATTER OF LIFE OR DEATH by Joao Passos (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11690165.txt.
Description
Joao Passos presents a talk summary on cell senescence and the role of mitochondria, published in 2024. Senescent cells have stopped dividing for good and release a mix of inflammatory signals. As these cells build up in tissues, they drive dysfunction and many diseases of aging. No single marker identifies them, which makes them hard to study and target. Faulty mitochondria, the cell's power plants, form a key part of the picture.
The talk first covers new efforts to map senescent cells in tissues, including imaging aided by AI. It then explains how mitochondria feed both the growth arrest and the inflammatory output of these cells. Mitochondria also help senescent cells resist death. Passos argues that a detailed map of mitochondrial behavior in senescence is needed to design therapies against cell aging.
Catalog record
| CREATOR | Joao Passos |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |