CHANGE IN ALZHEIMER’S DISEASE BLOOD-BASED BIOMARKERS AND ASSOCIATIONS WITH BRAIN AMYLOID DEPOSITION
James Pike, Yifei Lu, Jinyu Chen, Keenan Walker, Kevin Sullivan, Michael Griswold, Thomas Mosley, Priya Palta · 2024
Read CHANGE IN ALZHEIMER’S DISEASE BLOOD-BASED BIOMARKERS AND ASSOCIATIONS WITH BRAIN AMYLOID DEPOSITION by James Pike, Yifei Lu, Jinyu Chen, Keenan Walker, Kevin Sullivan, Michael Griswold, Thomas Mosley, Priya Palta (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11689400.txt.
Description
James Pike and co-authors studied in 2024 whether blood markers for Alzheimer disease in midlife predict later brain amyloid build-up. Blood tests promise a cheap, gentle way to track the disease across life. Stored samples came from a community study, taken in midlife and again in late life.
Brain scans in 2014 and 2015 sorted who had amyloid build-up. Midlife marker levels alone did not predict that outcome. Late-life levels of three markers did, as did change over time for two of them. Using all measures from both ages sorted cases best, though late-life measures alone came close. The authors call for more long-term work.
Catalog record
| CREATOR | James Pike, Yifei Lu, Jinyu Chen, Keenan Walker, Kevin Sullivan, Michael Griswold, Thomas Mosley, Priya Palta |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |