IMPACT OF EXERCISE/PHYSICAL ACTIVITY ON HEALTH SPAN: FROM MOLECULAR MECHANISMS TO FUNCTIONAL BENEFITS

Roger Fielding · 2024

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Description

Roger Fielding reviews how exercise defends health span, the years lived in working order, against the muscle decay of aging. With age, muscle shrinks and weakens across species, driven by faltering contractile proteins, metabolic drift, and dimmer nerve activation. Gene activity, epigenetic marks, and mitochondria all shift underneath.

The hopeful half of the lecture: much of that machinery still answers to movement. Regular activity, started even late in life, blunts or reverses losses in mass and function. The payoff reaches past muscle to diabetes, heart disease, cognition, frailty, and disability. Fielding connects molecular levers to functional gains to argue activity is a broad-spectrum intervention.

Catalog record

CREATORRoger Fielding
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11689381

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