ALZHEIMER’S DISEASE GENOMIC, BIOLOGIC, AND BEHAVIORAL PATHWAYS AMONG EXCEPTIONAL LONGEVITY FAMILIES

Mary Wojczynski, Stephanie Cosentino, Nalini Raghavachari · 2024

Read ALZHEIMER’S DISEASE GENOMIC, BIOLOGIC, AND BEHAVIORAL PATHWAYS AMONG EXCEPTIONAL LONGEVITY FAMILIES by Mary Wojczynski, Stephanie Cosentino, Nalini Raghavachari (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11689215.txt.

Description

Mary Wojczynski, Stephanie Cosentino, and Nalini Raghavachari introduce a 2024 symposium on Alzheimer's disease in very long-lived families. Some families produce many members who live exceptionally long lives, and studying them may reveal what protects the brain. The symposium draws on a large family study funded by the national aging institute.

That study enrolled nearly five thousand people from over five hundred two-generation families. Visits measured physical ability, thinking, and blood markers, and blood samples fed gene scans and other molecular tests. The symposium talks cover gene, body, and behavior paths to Alzheimer's disease within these families. One talk warns that risk scores built on the general public may mislead in such special groups. Another tracks how risk factors change over time. Together the talks use an unusual population to ask why some minds stay sharp into very old age.

Catalog record

CREATORMary Wojczynski, Stephanie Cosentino, Nalini Raghavachari
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE2 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11689215

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