SKELETAL MUSCLE MITOCHONDRIAL RESPIRATION ASSOCIATES WITH COGNITIVE FUNCTION IN OLDER ADULTS
Caterina Rosano, Stephen Kritchevsky, Iva Miljkovic, Anne Newman, Peggy Cawthon, Stephen Cummings, Paul Coen · 2024
Read SKELETAL MUSCLE MITOCHONDRIAL RESPIRATION ASSOCIATES WITH COGNITIVE FUNCTION IN OLDER ADULTS by Caterina Rosano, Stephen Kritchevsky, Iva Miljkovic, Anne Newman, Peggy Cawthon, Stephen Cummings, Paul Coen (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11689137.txt.
Description
Caterina Rosano and co-authors link muscle energy production to thinking speed in older adults in a 2024 study. Muscles with weak energy factories have been tied to poorer cognition, but prior work relied on indirect scan measures. This study added direct measures from muscle biopsies.
The sample held eight hundred fifty-eight adults averaging seventy-six years, drawn from a study of muscle, mobility, and aging. Biopsy-based respiration and scan-based capacity were each compared with a symbol substitution test and a general cognition test. Lower biopsy respiration tracked slower processing speed, even after accounting for health and body factors. The scan measure showed no clear link. The results hint that muscle energetics and brain speed age together.
Catalog record
| CREATOR | Caterina Rosano, Stephen Kritchevsky, Iva Miljkovic, Anne Newman, Peggy Cawthon, Stephen Cummings, Paul Coen |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |