A REAL-WORLD PHARMACOVIGILANCE STUDY OF SACUBITRIL\VALSARTAN IN OLDER PEOPLE
Zheng Kuai, Yu Hu · 2024
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Description
Zheng Kuai and Yu Hu present a 2024 real-world safety study of a heart drug pair in older adults. The pair, sacubitril and valsartan, leads care for weak hearts and high pressure, but old-age harm data were thin. The team mined a world report store with four signal-hunting methods. Over ninety-four thousand linked cases came in, and eighty-six harm terms stood out in the over-65 group after the hunt.
Known harms like jaw swelling, low pressure, kidney strain, and high potassium matched trial rates. Rare signals touched thinking and fragility, and one broad injury class showed only in the older group. Most cases landed in the first month of use. Fresh users past 65 earn close early watch, the data say.
Catalog record
| CREATOR | Zheng Kuai, Yu Hu |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |