Causal relationship between gut microbiota and androgenetic alopecia: A Mendelian randomization study
Jinyue Liu, Wenrong Luo, Zheyuan Hu, Xiaohai Zhu, Lie Zhu · 2024
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Description
Hair loss of the common patterned kind may be tied to gut microbes, and a 2024 study by Jinyue Liu and co-authors tests whether that link is causal. The team used Mendelian randomization, a method that uses gene variants as natural tests to sort cause from mere correlation.
They drew gut microbe data from a large study covering 211 taxa, from phyla down to genera, and gene data on hair loss from a public database. Their checks looked for a causal path from predicted gut microbes to the hair loss trait. To guard the result, they ran checks for consistency and for signs that some gene variants acted through other paths. The work adds gene-level evidence to the gut-skin idea.
Catalog record
| CREATOR | Jinyue Liu, Wenrong Luo, Zheyuan Hu, Xiaohai Zhu, Lie Zhu |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 20 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |