Targeting hypoxia and angiogenesis in hepatocellular carcinoma: New insights and therapeutic strategies
Jia-Yi Du, Chu-Ting Zhang, Ting Li, Ya-Ping Li · 2024
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Description
Jia-Yi Du, Chu-Ting Zhang, Ting Li, and Ya-Ping Li comment on a recent study of liver cancer and a protein that helps tumors grow new blood vessels. Their piece was published in twenty twenty-four. The protein, called Ang-2, matters most where tumors lack oxygen, as liver tumors often do.
The authors trace how Ang-2 levels change as chronic liver disease turns into cancer, and how a low-oxygen switch in cells controls it. They weigh Ang-2 as an early blood sign that cancer has spread. They also discuss silencing that low-oxygen switch to lower Ang-2 and slow the change that lets cancer cells spread. The piece maps where this line of treatment research may go next for a common and deadly cancer.
Catalog record
| CREATOR | Jia-Yi Du, Chu-Ting Zhang, Ting Li, Ya-Ping Li |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 14 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |