Congenital hyperinsulinism in the Ukraine: a 10-year national study
Evgenia Globa, Henrik Thybo Christesen, Michael Bau Mortensen, Jayne A. L. Houghton, Anne Lerberg Nielsen, Sönke Detlefsen, Sarah E. Flanagan · 2024
Read Congenital hyperinsulinism in the Ukraine: a 10-year national study by Evgenia Globa, Henrik Thybo Christesen, Michael Bau Mortensen, Jayne A. L. Houghton, Anne Lerberg Nielsen, Sönke Detlefsen, Sarah E. Flanagan (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11686448.txt.
Description
Evgenia Globa and co-authors present the first national study of congenital hyperinsulinism in Ukraine. Their study appeared in 2024. In this rare condition, babies make too much insulin and their blood sugar can crash. The team gathered 41 patients from the national registry for 2014 to 2023. Genetic tests, special scans, and surgery were done with help from partners abroad.
Gene faults were found in about 86 percent of lasting cases. All of them sat in two genes that control insulin release. Cases that faded early had more varied causes, including two named syndromes. Of nineteen children who had surgery, most had the focal form of the disease, where one spot in the pancreas is at fault. Many recovered fully after surgery. The study gives Ukraine its first full picture of the condition.
Catalog record
| CREATOR | Evgenia Globa, Henrik Thybo Christesen, Michael Bau Mortensen, Jayne A. L. Houghton, Anne Lerberg Nielsen, Sönke Detlefsen, Sarah E. Flanagan |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |